Great topic and I am so pleased you are seeing some improvement!
To add my story, yes, some of us really do get better, but unless you win the drug lotto (and those people probably have never even found this forum, let alone lurk around on it), it usually takes a fair bit of trial and error, and matching lifestyle changes and complementary therapies with medication.
I’ve had some very good success, and nearly 7 years after onset, am finally in remission. I’ll give a brief rundown on my journey - to give some hope with also a dose of reality.
I’ve tried 3 DMARDs and 3 biologics, as well as a couple of NSAIDs and prednisone. The DMARDs were about as effective as sugar tablets. Prednisone worked, but I had to take doses too high, and at 37 I had the bones of a 60yo.
Finally got onto Enbrel a year after onset, weaning off prednisone at the same time. Excellent for the arthritis, fatigue, and depression, which was 80% better within weeks. Unfortunately between going on the Enbrel, and off the long-term prednisone, long-dormant inflammatory bowel disease was triggered. I was a healthy weight of 59kg, and lost 5kg within 2 months (not to mention the horrible symptoms), despite deliberately eating the highest calorie food I could stomach.
Onto Humira, so desperate I paid out of pocket for the loading doses, as these were not subsidised. Improvement was much slower, but by 3 months I was back up to around 80%. I had a good run on Humira for quite a while, but hadn’t put the lifestyle changes into place to really allow my body to return to health. It stayed this way for about two years, then slowly I started getting worse. Then, I started to get very unusual symptoms not associated with the arthritis. I put them down to stress, as it was a highly stressful period (not normal day-to-day stuff). Fast forward two years, and I’m finally doing something to reduce my stress, starting on making real changes in my life, and though I am starting to cope a lot better, the Humira was even less effective. The other symptoms had become life altering, so out of desperation I switched to Cimzia. In hindsight, for those last two years on Humira, I had been having an adverse reaction to it.
The switch to Cimzia was amazing. I hadn’t realised how bad the adverse reaction I’d been having was - it was crazy-making stuff, and sleeping 14 hours a day. Now I sleep 8 hours and feel refreshed, and my PsA is almost never more than 5 minutes of stiffness in the morning or after a long drive (actually perhaps that’s just cause I’m in my 40’s ), and I’m now even starting to horse ride again, not well (yet ), but I’m up to cantering and jumping will be in the next few weeks.
6 weeks after onset, my PsA was so bad that my feet and legs started to go numb and lose power, the physio said from inflammation pressing on my spinal column. I was googling wheelchairs.
It has been a rocky ride, or perhaps more accurately a roller coaster, but yes, most of us get better in one way or another. For me, I am grateful that even if I go back to the lows, I definitely have more skills now, and an altered lifestyle, that will allow me to cope with it better. I’m loving the highs though, the trick to the roller coaster is just to hang on and ride it. I almost forgot that, and very nearly didn’t make it here. Mostly, I have the wonderful people on here to thank for that