For a variety of reasons, I am at the stage of thinking it is time that I tried switching my biologic. I’ve been on Humira pretty successfully for nearly 5 years - but although things are not like they were before Humira, it just doesn’t seem quite like it is keeping up any more (and it seems I’ve had a slow decline for about the last year and a half…).
My Rheumatologist does not seem to believe that the fatigue and other symptoms I’m having are part of my PsA (or the mild IBD that I seem to have as a cross-over autoimmune disease), so I’m really not sure he is going to be terribly engaged in a conversation about which would be best to switch to. On the other hand, he is unlikely to stop me if I flat out request it, as the cost to the government is similar regardless, and the risks are also similar to Humira.
So, the three I am looking at are Remicade, Simponi, and Cimiza, because they all appear to have effectiveness for both PsA and Crohn’s, are approved medications in my case, and seem reasonably well known.
Other than the IV vs subcut injection comparisons, does anyone else have any knowledge, experience, or pointers about which one I should try? Or should I just find a 3-sided coin and jump right in?