If its acute, it might if the pain is the result of long term inflammation (nothing reverses permanent damage or osteo that results from long term inflammation) it may have some effect. The thing is NO biologic is effective against peripheral inflammation. Their greatest effect is axial. That is the main reason they are frequently paired with a DMARD such as MTX. You need both and in addition frequently either a low dose steroid and an NSAID is required as well. Where it gets complicated if pick one Bio, one NSAID, One Steroid, and one DMARD, you have 16 possible ways to combine those meds to get maximum effect. If you are choosing between the 3 DMARDs, 4 Bios, 1 steroid and 5 most common NSAID used for PsA, you have 169 ways to combine them to get maximum effect. Thus what we call here the “Gap” it takes time but over 80% of patients DO get relief in 14 months of trial and error.
This is where the experience and expertise of your Rheumy plays in. It is also why the pooch gets screwed if your present to you PCP or ER for “pain” and they react (most don’t anymore) If narcos ar added for pain NOTHING will work as your whole immune system is reset (even once) They will get there and usually within a year.
When dealing with enthisitis, IF you are not constantly following a stretching/exercise regime things rust into and there is no way to know if anything is working. Tight muscles, tendons etc will continue to cause pain even if your meds are working perfectly.
My number 2 daughter was on the pro tennis tour for several years (after winning a national championship in College and my number 3 son an NFL linebacker (mostly on the scout team) They had to work out DAILY for 5 - 6 hours, not to get in shape, or even stay in shape, (practice and play did that) but rather to keep those muscles and tendons from rusting. Those workouts were PAINFUL (but not as painful as not working out) and frankly is why they both left the sports they loved.
Carry a few extra pounds and pain levels will go up, overindulge in certain foods (high in sugar, gluten, nightshades etc) and pain levels will go up. Miss a day of stretching/exercise pain levels will skyrocket.
I’ve said this before, but its repeated more often than I have. There is plenty of hope, but the first thing one needs understand is that medications TREAT PsA (they don’t fix it) To control it is a full time job. Diet/lifestyle (weight control etc,) Medication, and movement are the three legs of the stool that supports you (a three legged stool if you never live on a farm is the MOST stable platform on rough ground, a four legged stool is always unstable unless the ground under is perfect) So make your plan simple. The more you add to it (supplements, devices etc) the higher the likelihood it won’t work.